Sam Moore qualified MBChB at the University of Cape Town in 1971, having served on the Medical Students Council and as Editor of the student research publication, Inyanga Appointments at Victoria Hospital were followed by some in Dublin and the Royal Postgraduate Medical School and Hammersmith Hospital, London. He obtained the Fellowship of the Royal College of Surgeons and returned to South Africa to take up a post at the University of Natal/King Edward-Hospital in 1976.
He served 8 years at the Scott Memorial Hospital, in rural Lesotho, undergoing training in laparoscopic techniques through the Johns Hospital Medical School, Baltimore USA. He returned to South Africa and completed training in General and Paediatric Surgery at the University of Cape Town (Groote Schuur and Red Cross Hospitals), completing a Doctor of Medicine (MD) degree in 1993.
In 1991, he was appointed Associate Professor in General / Paediatric Surgery, University of Stellenbosch and elevated to a full Professorship in 1995. He is a past President of the South African Association of Paediatric Surgeons and has served on numerous committees including being an Overseas Council member of BAPS for some years.
He is fairly well known both locally and Internationally for his research interests both in conditions affecting the Enteric nervous system and developmental aspects of cancer of childhood with a special interest in their genetics. He has published widely having 195 publications, 2 books, an E-book and a number of chapters to date. He has also acted as External examiner and consultant in Surgery for a number of other African institutions, including the Universities of Zimbabwe and Namibia.
He is married to Ann (nee Hofmeyr) and they have 4 children and 4 grandchildren. He retired as Head of Paediatric Surgery at the end of 2013, but remains active as a part time consultant with duties both in teaching and research.
He is the 2014 recipient of the Denis Browne Medal for an outstanding contribution to Paediatric surgery.