Iris van Rooij is a reproductive epidemiologist at the Radboud university medical center, Nijmegen, The Netherlands. Her research is mostly focused on the etiology of congenital malformations, especially anorectal malformations, but also the VACTERL association, hypospadias, cleft lip/palate, and renal anomalies. This interest originates from her doctoral dissertation in 2003 entitled: ‘Etiology of orofacial clefts, gene-environment interactions and folate’. She coordinates the multidisciplinary AGORA data- and biobank of children with congenital malformations or childhood cancer in the Radboudumc. She integrates both genetic and pregnancy-related/environmental factors in her etiologic projects. Recently, she is partly shifting the focus towards pediatric care for patients with congenital malformations, including prognostic research, personalized healthcare, and prevention. She is vice-chair of the European Consortium ARM-Net (www.arm-net.eu), a network of peadiatric surgeons, patient organizations, and researchers that puts its efforts into improving the care of patients with anorectal malformations and stimulates scientific research in this area.